Volume 10 | Issue 1 |

 Abstract

Hamatological changes as impediments in the fish Catla catla (Hamilton) exposed in the laboratory conditions (in vivo) due to the Dichlorvos an organo phosphate, both technical grade and 76% EC (Nuvan) are studied. The fish blood parameters studied includes erythrocytes (RBC), White blood corpscules (WBC), Haemoglobin (Hb), Haematocrit value (Hct & PCV), Mean corpuscular volume (MCV), Mean corpsuclar Haemoglobin (MCH) and Mean corpsuclar haemoglobin concentration (MCHC) of which the first four are analysed to determine them quantitatively and the last three are determined as by calculation. The RBC, Hb and HCt decreased whereas WBC increased and accordingly the calculated and MCV, MCH and MCHC are too varied. Due to the toxic stress the blood regeneration of components failed to function normally and to cope the toxic action leucocytes increased. The effects of the pesticide of technical grade and 76% EC (Nuvan) both in lethal and sublethal concentration had a significant impact and in total the metabolism is impaired hence the growth will be limited as the fish is for culture candidate species.

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 Keywords

Catla catla, Dichlorvos, Technical Grade, 76% EC Nuvan, Sublethal, lethal, blood, RBC, WBC, Hb, Hct or PCV, MCV, MCH and MCHC..

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Creative Commons Attribution 4.0 and The Open Definition

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In this paper,we introduce the concept of fuzzy Supra Strongly Hyperconnected Spaces are studied. Finding the relations between fuzzy Supra Strongly Hyperconnected Spaces and other fuzzy Supra topological spaces. Illustrate the concept with suitable examples.

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 Keywords

Fuzzy Supra nowhere dense set, fuzzy Supra first category Space-, fuzzy Supra P-space, fuzzy Supra submaximal space, fuzzy Supra Hyperconnected space.

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Creative Commons Attribution 4.0 and The Open Definition

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Adjustment, General Intelligence, Gender, Undergraduate students

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Key words: Immunization, knowledge, ASHA worker, AWW, ANM.

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Creative Commons Attribution 4.0 and The Open Definition

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KEY WORDS - Alternative; 3R's; Toxicity

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Creative Commons Attribution 4.0 and The Open Definition

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Keywords: love token, distressed, lamenting, apsara, bond of love.

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Creative Commons Attribution 4.0 and The Open Definition

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The paper deal with study of models of load bearing wall structure. This Masonry load bearing wall subjected to vertical concentric and eccentric loading may led to collapse through instability. In this paper the failure pattern of masonry load bearing wall of different sizes were investigated via testing shaking table test , compressive strength . The result shows that the bearing wall cannot carry heavy loads but by increasing thickness their is possibility of less damage in the structure.

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 Keywords

Compressive, Shaking Table, Bearing Wall

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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 Keywords

QSPR, multiple linear regression (MLR), Aqueous solubility , Partition coefficient.

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 Abstract

Anti-platelet compounds are an important drug for cardiovascular diseases and for certain surgical procedures where a risk of stroke or thrombosis. Mer is a member of the TAM (Tyro3, Axl and Mer) receptor tyrosine kinase (RTK) subfamily with growth-arrest-specific-6Gas6) as one of the endogenous ligands. Currently, Mer has been shown to play important roles in regulating macrophage activity and platelet aggregation. The role of Mer kinase in regulating the second phase of platelet activation generates an opportunity to use Mer inhibitors for preventing thrombosis with diminished likelihood for bleeding as compared to current therapies. The QSAR tries to explain the observed variance in the biological effect of certain classes of compounds as a function of molecular changes caused by the substituents. These physiochemical descriptors which included parameters to account for hydrophobicity, electronic properties and steric effect are determined empirically or, more recently, by computational methods. QSAR methodologies save resources and expedite the process of the development of new molecules and drugs. In our works, we calculated many descriptors from the 43 molecular structures in literature1 by the software Dragon, MLR Methods was used to select descriptor and set up linear model. Then we developed a new QSAR model to explore the IC50 of anti-thrombosis the compounds with diverse structures. The square of correlation coefficient (R2) for best model with penta molecular descriptors after deletion of three compound is 0.9326. The best model since the values R = 0.9657, R2 = 0.9326 , R2A = 0.9227 , R2cv = 0.9325 are the best as compared to all the models. The calculated F value is greater than F theoretical value , the value of standard error of estimate is the lowest , SE = 0.5655, PRESS/SSY = 0.06743 confirms that it is statistically significant and excellent model and it has been found to be having outstanding predictive power also. The present finding the based on QSAR are in excellent agreement with the result obtain by Linhao Xu et al.

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 Keywords

QSAR, Anti-platelet compounds, Thrombosis using Mer, tyrosine kinase inhibitors.

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Creative Commons Attribution 4.0 and The Open Definition

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Online crime reporting system came up with the solution to replace the old manual complaint registration system. The victims can file the case and submit the evidence under the various sections on a single website. This project provides features like anonymous tip, alert systems, case status, crime notice board, cybercrime complaint registration, GPS tracking system, police contact details with the station address, and provide the safe storage for storing evidence and files and maintain a backup of every single data which helps the police to investigate the case and provide justice to victims in a meantime.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Anonymous tip, File Backup, Crime alert, Cyber complaint.

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Creative Commons Attribution 4.0 and The Open Definition