Volume 12 | Issue 9 |

 Abstract

This article delves into the fusion of GraphQL with AWS serverless design, presenting a guide for developers and architects interested in using these technologies for web applications. It starts by introducing GraphQL and discussing its benefits compared to REST APIs. The article then explores how AWS services like Lambda, API Gateway, and DynamoDB can create efficient and cost-effective serverless applications. Using explanations, illustrations, and step-by-step instructions, the piece emphasizes considerations and best practices to enhance performance, ensure security, and manage expenses in a serverless setting. Moreover, it tackles issues such as start latency and data management while offering practical solutions to overcome these challenges. In addition, the article discusses subjects such as combining Graph AI with AWS services, the function of GraphQL resolvers in serverless designs and utilizing Apollo GraphQL to create efficient and scalable APIs. By the end of it, readers will have an understanding of implementing and optimizing GraphQL within a serverless framework, along with insights into trends and potential advancements in this dynamic domain.

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GraphQL, AWS Serverless Architecture, AWS Lambda, API Gateway, DynamoDB, Cloud Computing, Web Development, Performance Optimization, Security.

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Creative Commons Attribution 4.0 and The Open Definition

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Senna occidentalis L. is a medicinal plant known for its traditional use in various therapeutic applications. In this study, we aimed to elucidate the metabolite profile of Senna occidentalis L. root extract using Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). The phytochemical composition of the extract was analyzed to identify and characterize the bioactive compounds present. The GC-MS analysis revealed a diverse array of volatile and non-volatile compounds in the Senna occidentalis L. root extract, including alkaloids, terpenoids, flavonoids, and other secondary metabolites. LC-MS/MS further provided a comprehensive identification of the polar and non- polar constituents, allowing for a more in-depth understanding of the chemical composition. To explore the potential therapeutic applications of the identified compounds, the antimicrobial activities of the Senna occidentalis L. root extract was evaluated against a panel of pathogenic microorganisms. The extract exhibited notable antimicrobial effects, demonstrating its efficacy against both Gram-positive and Gram-negative bacteria, as well as fungi. The findings from this study contribute valuable insights into the chemical composition of Senna occidentalis L. Roots and highlight its potential as a source of bioactive compounds with antimicrobial properties. Further research is warranted to isolate and characterize specific compounds responsible for the observed activities, paving the way for the development of novel pharmaceuticals or natural products for therapeutic applications.

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Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography- Mass Spectrometry (LC-MS/MS), Phytochemical, Antimicrobial properties.

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In the past few decades industrialization, urbanization, modernization, globalization and the rapid growth of information technology have produced myriad challenges. They have made a powerful impact on different segments of societies everywhere. It has been argued that any development resulting from globalization should be seen not merely as economic development, but also in terms of how it influences the relationships within the family as well as all other social and cultural aspects of life in a society. The problem posed to global society today ranges from survival to sustainable development and peace. This paper aims to study the impact of globalization on Indian family. It can be viewed in two ways. One may argue that in the era of economic restructuring through World Bank, WTO and IMF led policies of liberalization, privatization and globalization the family is emerging as a much stronger institution than ever before. The alternative point of view is that as a result of globalization, the institution of family is becoming progressively weaker as individualism grows. The rapid increase in the mobility of younger generation as they search for new employment and educational opportunities weakens the family structure. Functionally, distance renders it impractical for the members of a unit to come together as often as earlier. This affects the earlier idealized notion of the 'family' as the caring and the nurturing unit for children, the sick and elderly. The growing costs of education and health services and the new job opportunities opened up for the women outside the house once again brought the role of 'family' into question. In India, men, women and children, irrespective of caste, creed, religion and class, look to the family for assistance during troubled times, when they are sick or need some rest. Under the economic conditions fostered by liberalized markets, the socio-cultural relationships within the family are also undergoing a dramatic change.

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Kinship, Marriage, Family, Relationship

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Creative Commons Attribution 4.0 and The Open Definition

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Today, the new approach to pharmaceutical quality is called Quality by Design. The following paper provides an overview of pharmaceutical quality by design (QbD) and explains the various software tools and applications that are employed in QbD.The goal of pharmaceutical development is to create high-quality products and manufacturing processes that reliably produce the desired results. Products cannot be assessed for quality; instead, quality should be included into the design. The study analyses the current QbD-assisted software's, such as design- experts, Minitab fusion product development

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Creative Commons Attribution 4.0 and The Open Definition

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In the era of digital media, the rapid increase in video content generation and consumption poses a significant challenge for users seeking to extract valuable information efficiently. This project aims to develop an AI-powered real-time video summarization system that leverages advanced machine learning and natural language processing techniques to provide concise and accurate summaries of YouTube video content. By integrating OpenCV for video processing, deep neural networks for feature extraction, and state-of-the-art NLP models for summarization, the system generates brief summaries highlighting key points and essential information. Utilizing Streamlit for a user-friendly web interface, the system is designed for scalability and performance, ensuring it can handle diverse video types and lengths while delivering prompt summaries to enhance users' ability to quickly grasp video content.

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Video Summarization, Deep Learning, Natural Language Processing, Machine Learning, OpenCV, YouTube Data API, Streamlit, Deep Neural Networks, Feature Extraction, Text Summarization, Automatic Speech Recognition, Extractive Summarization, Abstractive Summarization, Video Processing, Real-time Systems

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Oral mucositis is a common, debilitating symptom affecting many patients on high-dose chemotherapy. It has been shown to affect 5-15% of patients undergoing cancer treatment in general, but with certain agents such as 5-florouracil (5FU), the rates are much higher, approaching 40-50%. Statement of the Problem: A study to assess the effectiveness of ice cube application in reducing oral mucositis among chemotherapy receiving patients in selected hospital at kanyakumari district. Objectives: To assess the level of oral mucositis before the application of ice cubes among chemotherapy receiving patients with cancer. To assess the level of oral mucositis after the application of ice cubes among chemotherapy receiving patients with cancer. Methodology:This study adopts quasi experimental design with pretest and post test control group design. Data was collected from 40 samples by simple random technique. The tool used for data collection include: Selected demographic variables, World Health Organization (WHO) scale gradings. All tools were validated and subjected to reliability testing. Pilot study was conducted to find out the feasibility of the study. The tool was administered and data was collected for 6 weeks from 40 samples and the data obtained were classified, grouped and analyzed based on the objectives and hypotheses formulated for the study using descriptive and inferential statistics. Results: In experimental group 35% of sample subjects had normal and mild oral mucositis, 20% had moderate and 10% severe erythema, were as in control group 40% of sample subjects had extreme oral mucositis, 30% had severe, 20% had moderate and 10% had mild erythema. The mean oral mucositis score in experimental group (1.0) was greater than the mean oral mucositis score of the control group (0.8). The mean difference was (0.2) and was significant at (P<0.001) level. Conclusion: The study findings revealed that, there was a high significance in reduction of oral mucositis among chemotherapy receiving patients after application of ice cubes in experimental group than control group. Thus ice cube application played an important role in reducing oral mucositis among chemotherapy receiving patients.

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Oral mucositis, ice cube application, chemotherapy

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Creative Commons Attribution 4.0 and The Open Definition

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The emergence of cloud computing has revolutionized the Information and Communication Technology landscape, offering a cost-effective and scalable solution for the on-demand provision of computing resources. Organizations are increasingly drawn to the cloud for outsourcing their computational requirements, benefiting from minimal upfront investment. Central to this paradigm are Service Level Agreements (SLAs), which ensure Quality of Service (QoS) between cloud providers and users. The breach of SLAs can result in contractual penalties and revenue loss, underscoring the criticality of effective SLA management for cloud providers. This involves continuous monitoring and control of various SLA parameters to prevent violations. To address this challenge, there is a growing need for proactive measures to anticipate and mitigate potential breaches by predicting SLA parameter values based on continuous monitoring data. In this research, we propose an agent-based SLA management framework featuring a coordinator agent designed to employ predictive modeling techniques for pre-emptively identifying and addressing SLA violations. Our approach is substantiated by a case study utilizing real-world datasets, demonstrating the efficacy of predictive modeling in enhancing SLA management within cloud environments.

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Creative Commons Attribution 4.0 and The Open Definition

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Service Level Agreement (SLA), Cloud computing, Agent based Computing. Multi agent system (MAS)

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Creative Commons Attribution 4.0 and The Open Definition

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Hypertension (HTN) is taken into consideration one of the main reasons of extended cardiovascular disease. Lowering blood stress does lessen cardiovascular risks; retaining systolic blood stress of much less than a hundred thirty mm Hg screen prevents headaches in sufferers with coronary heart failure, diabetes, coronary artery disease, stroke, and different cardiovascular diseases. This hobby discusses the pointers for deciding on the correct antihypertensive medicinal drugs . It affords the one-of-a-kind training for first, second, and third-line remedies for high blood pressure and highlights the indicators and aspect effects. It highlights the research completed to evaluate one-of-a-kind training of antihypertensive medicinal drugs and indicators for every magnificence .The 2017 American College of Cardiology (ACC) and American Heart Association (AHA) definition of HTN tiers is: Normal blood stress (BP): systolic BP is much less than a hundred and twenty , and diastolic BP is much less than eighty .Elevated BP: systolic BP is a hundred and twenty to a hundred thirty , and diastolic BP is much less than eighty . Stage 1 HTN: systolic BP a hundred thirty to 139 or diastolic BP eighty to 89. Stage 2 HTN: systolic BP as a minimum a hundred and forty or diastolic as a minimum 90. Hypertensive crises: systolic BP over a hundred and eighty and/or diastolic BP over a hundred and twenty . In the 2019 ACC/AHA Guideline at the Primary Prevention of Cardiovascular Disease, all sufferers with extended blood stress are encouraged to have life-style adjustments as preliminary remedy , which includes weight loss, a healthful coronary heart diet, extended bodily hobby , a low sodium diet, and dilemma of alcohol consumption.

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Tachycardia, B-blocker, Thiazide, Channel blocker, Dbumetanide, Torsemide

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Creative Commons Attribution 4.0 and The Open Definition

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This paper attempts to study the role of women in recreating the space in the process of resettling in the outskirts of Calcutta. If Partition has destroyed a whole generation of women, it has also provided an opportunity for many women to move into the public sphere which was even unimaginable to many women before Partition. Such large-scale displacement of women made the country think about workplaces where women were a new presence and on political mobilization where women began to participate in great numbers. not all women welcomed this newfound independence. This individual freedom was also a form of slavery, a burden which one can neither carry, nor avoid. Women's dominion, sphere, and location have always been inside the house and have been connected, across time and cultures, to a private world apart from a public one inhabited by males. Compared to their male compatriots, women were far more vociferous. Since they were more receptive to criticism and more eager to speak out against the system when surrounded by supportive individuals, refugee women were the first to organise. Even the screaming fits that hungry kids would throw at home had to be dealt with. This is how women started to take care of both the outside world and their homes. Hindu refugee women gradually started to make their public debuts.

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refugee, women, partition, public, workplace

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Creative Commons Attribution 4.0 and The Open Definition

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Abstract: The period before parturition is honoured as a precarious occasion, posing raised troubles for the emergence of psychiatric conditions, whether pre-existing or recently evolved. On a global scale, current mental health conditions similar to depression and anxiety significantly contribute to maternal morbidity and mortality, representing a substantial challenge. This burden is particularly pronounced in low- and middle-income nations. Objectives: 1. To assess the level of anxiety and depression among antenatal mothers. 2. To assess the correlation between anxiety and depression among antenatal mothers. 3. To find the association between the level of anxiety and depression with selected demographic variables among antenatal mothers. Methodology: A quantitative research approach and descriptive research design was used. 100 antenatal mothers from Antenatal OPD, Thiruvallur Government Medical College and Hospital, were selected as a study sample by using a non-probability purposive sampling technique. The investigator collected data using the self-administered Perinatal Anxiety Screening Scale (PASS) and Edinburg Postnatal Depression Scale (EPDS) to assess anxiety and depression among antenatal mothers. The data was analysed using descriptive and inferential statistics. Results: The study results showed that the majority 73(73%) had mild to moderate anxiety, 17(17%) had asymptomatic, and 10(10%) had severe anxiety. While 35(35%) had likely not had depression,25(25%) had probable depression and 10(10%) had a fairly high possibility of depression. While positive correlation (r=0.708) between anxiety and depression. Conclusion: The findings of the study indicated that most mothers experienced anxiety and depression during pregnancy and also reveal a positive correlation between anxiety and depression. The study finding highlights the importance for healthcare professionals and policymakers to screen for mental health issues, implement targeted interventions, and enhance antenatal care services.

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 Keywords

Antenatal Mother , Anxiety, Depression

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Creative Commons Attribution 4.0 and The Open Definition